COVID-19 test should track viral load too, says new ICMR study

New Delhi: Only seven per cent of coronavirus samples have a ‘high viral load’, that means these individuals would, on common, transmit the an infection to six.25 different individuals.

The overwhelming majority of 84 per cent have a low degree of infectiousness, transmitting to solely 0.eight individuals on common. Nine per cent have a average viral load.

Viral load refers back to the amount of a virus in an organism and is a mirrored image of how rapidly the virus is replicating.

These are new findings by the ICMR’s National Institute of Occupational Health (NIOH), Ahmedabad, primarily based on a study of over 1,000 samples collected in Gujarat in April and May.

The outcomes might be submitted to ICMR’s Indian Journal of Medical Research (IJMR) this week and underline the necessity to embrace viral load figures in COVID-19 test reviews.

This assumes significance provided that many who test constructive for coronavirus are asymptomatic.

“With the burden we are seeing in Gujarat, we should test for viral load and quarantine the ‘super-spreaders’. We have observed that viral load is a very strong determining factor. Few people spread most infections and most people spread very few infections — this has been observed in our study,” a prime official of the institute mentioned.

One indicator of viral load is “Ct value” or cycle threshold.

RT-PCR assessments for Covid use fluorescent indicators to detect nucleic acids. Ct worth is the variety of cycles required within the machine for the fluorescent signalling to cross the bottom degree of the machine. A low worth, subsequently, means a excessive viral load and vice versa.

READ ALSO :  UN concerned over chances of coronavirus pandemic 3rd wave in India

“RT-PCR results as of now give positive and negatives but we also should report the Ct (cycle threshold) value. With that value, we can identify high, moderate, or low viral load. It is automatically given in the RT-PCR test anyway, but we need to change our testing policy so this value is also collected by the testing labs,” the official added.

Source hyperlink

Give a Comment